DNA binding ability and MTHFR inhibitory activity of β Carboline harmaline of Alangium salviifolium on MCF-7
نویسنده
چکیده
Plant and plant products are the major source for the discovery of new drugs. Alangium salviifolium utilized in traditional medicine has resourceful medicinal properties.The aim of present study was to evaluate the biological activity of alkaloid β Carboline harmaline of Alangium salviifolium in cell growth activity inhibition. The potentiality of the alkaloid compound in inhibition of MTHFR with increased cytotoxicity in vitro was detrmined β Carboline harmaline of Alangium salviifolium at 320μm concentration exhibtited MTHFR and cell growth inhibitory activity. The result suggested alkaloid β Carboline harmaline of Alangium salviifolium can be used as potential chemotherapeutic drug.
منابع مشابه
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